Adrenomedullin Amidation Enzyme Activities in Hypertensive Patients.
نویسندگان
چکیده
منابع مشابه
Changes in cardiac adrenomedullin concentration in renovascular hypertensive rats.
We assessed changes in tissue and plasma adrenomedullin levels in two-kidney, one-clip renovascular hypertensive rats. Four weeks after clipping, adrenomedullin concentrations were significantly higher in the cardiac ventricles and lower in the left atrium than the respective values in sham-operated rats. The left ventricular adrenomedullin concentration significantly correlated with systolic b...
متن کاملLong-term adrenomedullin infusion improves survival in malignant hypertensive rats.
Previous studies have demonstrated that adrenomedullin has inhibitory effects on the proliferation and DNA synthesis of mesangial cells and vascular smooth muscle cells in vitro and that plasma adrenomedullin levels are markedly elevated in malignant hypertension. This study was designed to examine whether chronic adrenomedullin infusion has renoprotective effects in malignant hypertensive rats...
متن کاملEffect of physical activities and obesity on Ramadan fasting among hypertensive patients
Objective: To find out the effect of physical activities and obesity among Ramadan fasting hypertensive patients of Karachi. Methods: 117 hypertensive patients were selected conveniently from the staff and faculty members of Dow University and other locations of Karachi. The inclusion criterion was the hypertensive patients with at least 20 days of fasting. The investigators visited three times...
متن کاملBiosynthetic enzyme activities and catecholamines in adrenal glands of genetic and experimental hypertensive rats.
The activities of catecholamine-synthesizing enzymes in adrenal glands have been investigated during the development of high blood pressure in spontaneously hypertensive rats (SHR) and in rats made hypertensive by administration of DOCA and saline. There was a significant decrease in the activity of tyrosine hydroxylase, dopamine-/?-hydroxylase, and phenylethanolamine N-methyltransferase in you...
متن کاملExpression of adrenomedullin and peptide amidation activity in human prostate cancer and in human prostate cancer cell lines.
After therapeutic hormone deprivation, prostate cancer (CaP) cells often develop androgen-independent growth through not-well-defined mechanisms. The presence of neuroendocrine (NE) cells is often greater in prostate carcinoma than in normal prostate, and the frequency of NE cells correlates with tumor malignancy, loss of androgen sensitivity, increase of autocrine-paracrine activity, and poor ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hypertension Research
سال: 2000
ISSN: 0916-9636,1348-4214
DOI: 10.1291/hypres.23.167